Implementing Genomic Clinical Decision Support for Drug‐Based Precision Medicine

The explosive growth of patient‐specific genomic information relevant to drug therapy will continue to be a defining characteristic of biomedical research. To implement drug‐based personalized medicine (PM) for patients, clinicians need actionable information incorporated into electronic health reco...

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Detalles Bibliográficos
Autores principales: Freimuth, RR, Formea, CM, Hoffman, JM, Matey, E, Peterson, JF, Boyce, RD
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351408/
https://www.ncbi.nlm.nih.gov/pubmed/28109071
http://dx.doi.org/10.1002/psp4.12173
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author Freimuth, RR
Formea, CM
Hoffman, JM
Matey, E
Peterson, JF
Boyce, RD
author_facet Freimuth, RR
Formea, CM
Hoffman, JM
Matey, E
Peterson, JF
Boyce, RD
author_sort Freimuth, RR
collection PubMed
description The explosive growth of patient‐specific genomic information relevant to drug therapy will continue to be a defining characteristic of biomedical research. To implement drug‐based personalized medicine (PM) for patients, clinicians need actionable information incorporated into electronic health records (EHRs). New clinical decision support (CDS) methods and informatics infrastructure are required in order to comprehensively integrate, interpret, deliver, and apply the full range of genomic data for each patient.1
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spelling pubmed-53514082017-03-22 Implementing Genomic Clinical Decision Support for Drug‐Based Precision Medicine Freimuth, RR Formea, CM Hoffman, JM Matey, E Peterson, JF Boyce, RD CPT Pharmacometrics Syst Pharmacol Perspective The explosive growth of patient‐specific genomic information relevant to drug therapy will continue to be a defining characteristic of biomedical research. To implement drug‐based personalized medicine (PM) for patients, clinicians need actionable information incorporated into electronic health records (EHRs). New clinical decision support (CDS) methods and informatics infrastructure are required in order to comprehensively integrate, interpret, deliver, and apply the full range of genomic data for each patient.1 John Wiley and Sons Inc. 2017-03-15 2017-03 /pmc/articles/PMC5351408/ /pubmed/28109071 http://dx.doi.org/10.1002/psp4.12173 Text en © 2017 The Authors CPT: Pharmacometrics & Systems Pharmacology published by Wiley Periodicals, Inc. on behalf of American Society for Clinical Pharmacology and Therapeutics This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Perspective
Freimuth, RR
Formea, CM
Hoffman, JM
Matey, E
Peterson, JF
Boyce, RD
Implementing Genomic Clinical Decision Support for Drug‐Based Precision Medicine
title Implementing Genomic Clinical Decision Support for Drug‐Based Precision Medicine
title_full Implementing Genomic Clinical Decision Support for Drug‐Based Precision Medicine
title_fullStr Implementing Genomic Clinical Decision Support for Drug‐Based Precision Medicine
title_full_unstemmed Implementing Genomic Clinical Decision Support for Drug‐Based Precision Medicine
title_short Implementing Genomic Clinical Decision Support for Drug‐Based Precision Medicine
title_sort implementing genomic clinical decision support for drug‐based precision medicine
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351408/
https://www.ncbi.nlm.nih.gov/pubmed/28109071
http://dx.doi.org/10.1002/psp4.12173
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