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Building confidence in quantitative systems pharmacology models: An engineer's guide to exploring the rationale in model design and development
This tutorial promotes good practice for exploring the rationale of systems pharmacology models. A safety systems engineering inspired notation approach provides much needed rigor and transparency in development and application of models for therapeutic discovery and design of intervention strategie...
Autores principales: | Timmis, J, Alden, K, Andrews, P, Clark, E, Nellis, A, Naylor, B, Coles, M, Kaye, P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351409/ https://www.ncbi.nlm.nih.gov/pubmed/27863172 http://dx.doi.org/10.1002/psp4.12157 |
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