Novel multiple tyrosine kinase inhibitor ponatinib inhibits bFGF-activated signaling in neuroblastoma cells and suppresses neuroblastoma growth in vivo

Neuroblastoma (NB) is one of the most common pediatric malignancies in children. Abnormal activation of receptor tyrosine kinases contributes to the pathological development of NB. Therefore, targeting tyrosine kinase receptors to cure NB is a promising strategy. Here, we report that a multi-targete...

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Detalles Bibliográficos
Autores principales: Li, Haoyu, Wang, Yongfeng, Chen, Zhenghu, Lu, Jiaxiong, Pan, Jessie, Yu, Yang, Zhao, Yanling, Zhang, Huiyuan, Hu, Ting, Liu, Qing, Yang, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351597/
https://www.ncbi.nlm.nih.gov/pubmed/27564113
http://dx.doi.org/10.18632/oncotarget.11580

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