Gankyrin promotes epithelial-mesenchymal transition and metastasis in NSCLC through forming a closed circle with IL-6/ STAT3 and TGF-β/SMAD3 signaling pathway

Our previous research showed that Gankyrin was overexpressed in NSCLC and significantly associated with clinicopathologic features and poor prognosis. In this study, we will explore potential effect of Gankyrin on EMT and metastasis in NSCLC. The ectopic higher expression of Gankyrin markedly increa...

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Detalles Bibliográficos
Autores principales: Wang, Wu-ping, Sun, Ying, Lu, Qiang, Zhao, Jin-bo, Wang, Xue-jiao, Chen, Zhao, Ni, Yun-feng, Wang, Ju-zheng, Han, Yong, Zhang, Zhi-pei, Yan, Xiao-long, Li, Xiao-fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351600/
https://www.ncbi.nlm.nih.gov/pubmed/27992365
http://dx.doi.org/10.18632/oncotarget.13947

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