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Myostatin-deficiency in mice increases global gene expression at the Dlk1-Dio3 locus in the skeletal muscle
Myostatin, a member of the transforming growth factor-beta superfamily, is a negative regulator of skeletal muscle growth and development. Myostatin inhibition leads to increased skeletal muscle mass in mammals; hence, myostatin is considered a potential therapeutic target for skeletal muscle wastin...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals LLC
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351603/ https://www.ncbi.nlm.nih.gov/pubmed/27992376 http://dx.doi.org/10.18632/oncotarget.13966 |