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Idelalisib induces PUMA-dependent apoptosis in colon cancer cells

Idelalisib, a PI3K inhibitor, specifically targeting p110δ, has been approved for the treatment of chronic lymphocytic leukemia/small lymphocytic lymphoma and follicular lymphoma. However, the mechanisms of action of idelalisib in colon cancer cells are not well understood. We investigated how idela...

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Detalles Bibliográficos
Autores principales:	Yang, Shida, Zhu, Zhiyong, Zhang, Xiaobing, Zhang, Ning, Yao, Zhicheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351616/ https://www.ncbi.nlm.nih.gov/pubmed/28008149 http://dx.doi.org/10.18632/oncotarget.14043

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