PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression

Despite improvement of therapeutic treatments for breast cancer, the development of brain metastases has become a major limitation to life expectancy for many patients. Brain metastases show very commonly alterations in EGFR and HER2 driven pathways, of which PTEN is an important regulator. Here, we...

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Detalles Bibliográficos
Autores principales: Hohensee, Ina, Chuang, Han-Ning, Grottke, Astrid, Werner, Stefan, Schulte, Alexander, Horn, Stefan, Lamszus, Katrin, Bartkowiak, Kai, Witzel, Isabell, Westphal, Manfred, Matschke, Jakob, Glatzel, Markus, Jücker, Manfred, Pukrop, Tobias, Pantel, Klaus, Wikman, Harriet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351620/
https://www.ncbi.nlm.nih.gov/pubmed/28008153
http://dx.doi.org/10.18632/oncotarget.14047

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