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Combination treatment of prostate cancer with FGF receptor and AKT kinase inhibitors

Activation of the PI3K/AKT pathway occurs in the vast majority of advanced prostate cancers (PCas). Activation of fibroblast growth factor receptor (FGFR) signaling occurs in a wide variety of malignancies, including PCa. RNA-Seq of castration resistant PCa revealed expression of multiple FGFR signa...

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Detalles Bibliográficos
Autores principales:	Feng, Shu, Shao, Longjiang, Castro, Patricia, Coleman, Ilsa, Nelson, Peter S, Smith, Paul D, Davies, Barry R, Ittmann, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351622/ https://www.ncbi.nlm.nih.gov/pubmed/28008155 http://dx.doi.org/10.18632/oncotarget.14049

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