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Histone deacetylases 1 and 2 cooperate in regulating BRCA1, CHK1, and RAD51 expression in acute myeloid leukemia cells

Resistance to chemotherapy and a high relapse rate highlight the importance of finding new therapeutic options for the treatment of acute myeloid leukemia (AML). Histone deacetylase (HDAC) inhibitors (HDACIs) are a promising class of drugs for the treatment of AML. HDACIs have limited single-agent c...

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Detalles Bibliográficos
Autores principales:	Zhao, Jianyun, Xie, Chengzhi, Edwards, Holly, Wang, Guan, Taub, Jeffrey W, Ge, Yubin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351634/ https://www.ncbi.nlm.nih.gov/pubmed/28030834 http://dx.doi.org/10.18632/oncotarget.14062

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