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Discovery of a novel splice variant of Fcar (CD89) unravels sequence segments necessary for efficient secretion: A story of bad signal peptides and good ones that nevertheless do not make it

The IgA receptor, Fcar (CD89) consists of 5 sequence segments: 2 segments (S1, S2) forming the potential signal peptide, 2 extracellular EC domains that include the IgA binding site, and the transmembrane and cytoplasmic tail (TM/C) region. Numerous Fcar splice variants have been reported with vario...

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Detalles Bibliográficos
Autores principales:	Lua, Wai-Heng, Ling, Wei-Li, Su, Chinh Tran-To, Yeo, Joshua Yi, Verma, Chandra Shekhar, Eisenhaber, Birgit, Eisenhaber, Frank, Gan, Samuel Ken-En
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2017
Materias:	Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351921/ https://www.ncbi.nlm.nih.gov/pubmed/28103138 http://dx.doi.org/10.1080/15384101.2017.1281480

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