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Schizophrenia-associated methylomic variation: molecular signatures of disease and polygenic risk burden across multiple brain regions
Genetic association studies provide evidence for a substantial polygenic component to schizophrenia, although the neurobiological mechanisms underlying the disorder remain largely undefined. Building on recent studies supporting a role for developmentally regulated epigenetic variation in the molecu...
Autores principales: | Viana, Joana, Hannon, Eilis, Dempster, Emma, Pidsley, Ruth, Macdonald, Ruby, Knox, Olivia, Spiers, Helen, Troakes, Claire, Al-Saraj, Safa, Turecki, Gustavo, Schalkwyk, Leonard C., Mill, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351932/ https://www.ncbi.nlm.nih.gov/pubmed/28011714 http://dx.doi.org/10.1093/hmg/ddw373 |
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