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Peptide modification results in the formation of a dimer with a 60-fold enhanced antimicrobial activity
Cationic antimicrobial peptides (CAMPs) occur naturally in numerous organisms and are considered as a class of antibiotics with promising potential against multi-resistant bacteria. Herein, we report a strategy that can lead to the discovery of novel small CAMPs with greatly enhanced antimicrobial a...
Autores principales: | Thamri, Amal, Létourneau, Myriam, Djoboulian, Alex, Chatenet, David, Déziel, Eric, Castonguay, Annie, Perreault, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351969/ https://www.ncbi.nlm.nih.gov/pubmed/28296935 http://dx.doi.org/10.1371/journal.pone.0173783 |
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