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Spatial analysis improves the detection of early corneal nerve fiber loss in patients with recently diagnosed type 2 diabetes
Corneal confocal microscopy (CCM) has revealed reduced corneal nerve fiber (CNF) length and density (CNFL, CNFD) in patients with diabetes, but the spatial pattern of CNF loss has not been studied. We aimed to determine whether spatial analysis of the distribution of corneal nerve branching points (...
Autores principales: | Ziegler, Dan, Winter, Karsten, Strom, Alexander, Zhivov, Andrey, Allgeier, Stephan, Papanas, Nikolaos, Ziegler, Iris, Brüggemann, Jutta, Ringel, Bernd, Peschel, Sabine, Köhler, Bernd, Stachs, Oliver, Guthoff, Rudolf F., Roden, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352008/ https://www.ncbi.nlm.nih.gov/pubmed/28296936 http://dx.doi.org/10.1371/journal.pone.0173832 |
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