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Hyperglycemia triggers HIPK2 protein degradation

Homeodomain interacting protein kinase-2 (HIPK2) is an evolutionary conserved kinase that modulates several key molecular pathways to restrain tumor growth and induce p53-depending apoptotic cell-death in response to anticancer therapies. HIPK2 silencing in cancer cells leads to chemoresistance and...

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Detalles Bibliográficos
Autores principales:	Baldari, Silvia, Garufi, Alessia, Granato, Marisa, Cuomo, Laura, Pistritto, Giuseppa, Cirone, Mara, D'Orazi, Gabriella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352047/ https://www.ncbi.nlm.nih.gov/pubmed/27901482 http://dx.doi.org/10.18632/oncotarget.13595

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