Decreased 5-hydroxymethylcytosine levels correlate with cancer progression and poor survival: a systematic review and meta-analysis

Ten-eleven translocation (TET) enzymes catalyze the oxidation of 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC) and then to 5-formylcytosine (5-fC) and 5-carboxylcytosine (5-caC), resulting in genomic DNA demethylation. Decreased 5-hmC levels have been reported in a variety of cancers, a...

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Detalles Bibliográficos
Autores principales: Chen, Zhaoli, Shi, Xuejiao, Guo, Lanwei, Li, Yuan, Luo, Mei, He, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352110/
https://www.ncbi.nlm.nih.gov/pubmed/27911867
http://dx.doi.org/10.18632/oncotarget.13719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352110/
https://www.ncbi.nlm.nih.gov/pubmed/27911867
http://dx.doi.org/10.18632/oncotarget.13719

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