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Gastrin stimulates a cholecystokinin-2-receptor-expressing cardia progenitor cell and promotes progression of Barrett's-like esophagus
OBJECTIVE: The incidence of esophageal adenocarcinoma (EAC) is increasing, but factors contributing to malignant progression of its precursor lesion, Barrett's esophagus (BE), have not been defined. Hypergastrinemia caused by long-term use of proton pump inhibitors (PPIs), has been suggested as...
Autores principales: | Lee, Yoomi, Urbanska, Aleksandra M., Hayakawa, Yoku, Wang, Hongshan, Au, Andrew S., Luna, Aesis M., Chang, Wenju, Jin, Guangchun, Bhagat, Govind, Abrams, Julian A., Friedman, Richard A., Varro, Andrea, Wang, Kenneth K., Boyce, Malcolm, Rustgi, Anil K., Sepulveda, Antonia R., Quante, Michael, Wang, Timothy C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352112/ https://www.ncbi.nlm.nih.gov/pubmed/27448962 http://dx.doi.org/10.18632/oncotarget.10667 |
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