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A magnesium-induced triplex pre-organizes the SAM-II riboswitch
Our (13)C- and (1)H-chemical exchange saturation transfer (CEST) experiments previously revealed a dynamic exchange between partially closed and open conformations of the SAM-II riboswitch in the absence of ligand. Here, all-atom structure-based molecular simulations, with the electrostatic effects...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352136/ https://www.ncbi.nlm.nih.gov/pubmed/28248966 http://dx.doi.org/10.1371/journal.pcbi.1005406 |