Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4(+) versus CD8(+) T cells

Inappropriate activation or inadequate regulation of CD4(+) and CD8(+) T cells may contribute to the initiation and progression of multiple autoimmune and inflammatory diseases. Studies on disease-associated genetic polymorphisms have highlighted the importance of biological context for many regulat...

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Detalles Bibliográficos
Autores principales: Kasela, Silva, Kisand, Kai, Tserel, Liina, Kaleviste, Epp, Remm, Anu, Fischer, Krista, Esko, Tõnu, Westra, Harm-Jan, Fairfax, Benjamin P., Makino, Seiko, Knight, Julian C., Franke, Lude, Metspalu, Andres, Peterson, Pärt, Milani, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352142/
https://www.ncbi.nlm.nih.gov/pubmed/28248954
http://dx.doi.org/10.1371/journal.pgen.1006643

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