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Effects of dexamethasone coadministered with oseltamivir on the pharmacokinetics of oseltamivir in healthy volunteers

PURPOSE: Oseltamivir is widely used in the treatment and prophylaxis of influenza A and B viral infections. It is ingested as an oral prodrug that is rapidly metabolized by carboxylesterase 1 (CES1) to its active form, oseltamivir carboxylate. Dexamethasone is also used in the treatment of acute res...

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Detalles Bibliográficos
Autores principales:	Jang, Kyungho, Kim, Min-Kyoung, Oh, Jaeseong, Lee, SeungHwan, Cho, Joo-Youn, Yu, Kyung-Sang, Choi, Tai Kiu, Lee, Sang-Hyuk, Lim, Kyoung Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352149/ https://www.ncbi.nlm.nih.gov/pubmed/28331290 http://dx.doi.org/10.2147/DDDT.S124307

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