Cargando…
Inhibition of the transcriptional repressor complex Bcl-6/BCoR induces endothelial sprouting but does not promote tumor growth
The oncogenic potential of the transcriptional repressor Bcl-6 (B-cell lymphoma 6) was originally discovered in non-Hodgkin patients and the soluble Bcl-6 inhibitor 79-6 was developed to treat diffuse large B-cell lymphomas with aberrant Bcl-6 expression. Since we found Bcl-6 and its co-repressor BC...
Autores principales: | Buchberger, Elisabeth, Payrhuber, Dietmar, Harchi, Miriam El, Zagrapan, Branislav, Scheuba, Katharina, Zommer, Anna, Bugyik, Edina, Dome, Balazs, Kral, Julia Barbara, Schrottmaier, Waltraud Cornelia, Schabbauer, Gernot, Petzelbauer, Peter, Gröger, Marion, Bilban, Martin, Brostjan, Christine |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352177/ https://www.ncbi.nlm.nih.gov/pubmed/27880939 http://dx.doi.org/10.18632/oncotarget.13477 |
Ejemplares similares
-
Overexpression of the Transcriptional Repressor Complex BCL-6/BCoR Leads to Nuclear Aggregates Distinct from Classical Aggresomes
por: Buchberger, Elisabeth, et al.
Publicado: (2013) -
BCoR-L1 variation and breast cancer
por: Lose, Felicity, et al.
Publicado: (2007) -
Correction: BCoR-L1 variation and breast cancer
por: Lose, Felicity, et al.
Publicado: (2008) -
Enhanced endothelial motility and multicellular sprouting is mediated by the scaffold protein TKS4
por: Mehes, Elod, et al.
Publicado: (2019) -
Mutations in BCOR, a co-repressor of CRX/OTX2, are associated with early-onset retinal degeneration
por: Langouët, Maéva, et al.
Publicado: (2022)