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Toward the development of a novel non-RGD cyclic peptide drug conjugate for treatment of human metastatic melanoma
The newly discovered short (9 amino acid) non-RGD S-S bridged cyclic peptide ALOS-4 (H-cycl(Cys-Ser-Ser-Ala-Gly-Ser-Leu-Phe-Cys)-OH), which binds to integrin α(v)β(3) is investigated as peptide carrier for targeted drug delivery against human metastatic melanoma. ALOS4 binds specifically the α(v)β(3...
Autores principales: | Redko, Boris, Tuchinsky, Helena, Segal, Tamar, Tobi, Dror, Luboshits, Galia, Ashur-Fabian, Osnat, Pinhasov, Albert, Gerlitz, Gabi, Gellerman, Gary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352194/ https://www.ncbi.nlm.nih.gov/pubmed/27768593 http://dx.doi.org/10.18632/oncotarget.12748 |
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