Cargando…

Toward the development of a novel non-RGD cyclic peptide drug conjugate for treatment of human metastatic melanoma

The newly discovered short (9 amino acid) non-RGD S-S bridged cyclic peptide ALOS-4 (H-cycl(Cys-Ser-Ser-Ala-Gly-Ser-Leu-Phe-Cys)-OH), which binds to integrin α(v)β(3) is investigated as peptide carrier for targeted drug delivery against human metastatic melanoma. ALOS4 binds specifically the α(v)β(3...

Descripción completa

Detalles Bibliográficos
Autores principales:	Redko, Boris, Tuchinsky, Helena, Segal, Tamar, Tobi, Dror, Luboshits, Galia, Ashur-Fabian, Osnat, Pinhasov, Albert, Gerlitz, Gabi, Gellerman, Gary
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352194/ https://www.ncbi.nlm.nih.gov/pubmed/27768593 http://dx.doi.org/10.18632/oncotarget.12748

Ejemplares similares

Novel synthetic cyclic integrin αvβ3 binding peptide ALOS4: antitumor activity in mouse melanoma models
por: Yacobovich, Shiri, et al.
Publicado: (2016)

RGD-modified dihydrolipoamide dehydrogenase conjugated to titanium dioxide nanoparticles – switchable integrin-targeted photodynamic treatment of melanoma cells
por: Dayan, Avraham, et al.
Publicado: (2018)

Anti-Cancer Effects of Cyclic Peptide ALOS4 in a Human Melanoma Mouse Model
por: Levi, Bar, et al.
Publicado: (2021)

Gold nanoparticles stabilize peptide-drug-conjugates for sustained targeted drug delivery to cancer cells
por: Kalimuthu, Kalishwaralal, et al.
Publicado: (2018)

Three-Dimensional Modeling of Thyroid Hormone Metabolites Binding to the Cancer-Relevant αvβ3 Integrin: In-Silico Based Study
por: Tobi, Dror, et al.
Publicado: (2022)

The Heterochromatin Landscape in Migrating Cells and the Importance of H3K27me3 for Associated Transcriptome Alterations
por: Segal, Tamar, et al.
Publicado: (2018)

Novel Cyclic Peptides for Targeting EGFR and EGRvIII Mutation for Drug Delivery
por: Furman, Olga, et al.
Publicado: (2022)

Cyclic RGD-conjugated Pluronic(®) blending system for active, targeted drug delivery
por: Lim, Chaemin, et al.
Publicado: (2018)

Fast detection of deletion breakpoints using quantitative PCR
por: Abildinova, Gulshara, et al.
Publicado: (2016)

Novel Bifunctional Cyclic Chelator for (89)Zr Labeling–Radiolabeling and Targeting Properties of RGD Conjugates
por: Zhai, Chuangyan, et al.
Publicado: (2015)

Theranostic system for ratiometric fluorescence monitoring of peptide-guided targeted drug delivery
por: Rozovsky, Alex, et al.
Publicado: (2019)

Density-tunable conjugation of cyclic RGD ligands with polyion complex vesicles for the neovascular imaging of orthotopic glioblastomas
por: Kawamura, Wataru, et al.
Publicado: (2015)

Molecular Magnetic Resonance Imaging of Angiogenesis In Vivo using Polyvalent Cyclic RGD-Iron Oxide Microparticle Conjugates
por: Melemenidis, Stavros, et al.
Publicado: (2015)

Effect of multiple cyclic RGD peptides on tumor accumulation and intratumoral distribution of IRDye 700DX-conjugated polymers
por: Dou, Xuebo, et al.
Publicado: (2018)

Modeling of Biological Activity of PEO-Coated Titanium Implants with Conjugates of Cyclic RGD Peptide with Amino Acid Bisphosphonates
por: Parfenova, Lyudmila V., et al.
Publicado: (2022)

Radiolabeled cyclic RGD peptides as radiotracers for tumor imaging
por: Shi, Jiyun, et al.
Publicado: (2016)

Evaluating the Usefulness of a Novel (10)B-Carrier Conjugated With Cyclic RGD Peptide in Boron Neutron Capture Therapy
por: Masunaga, Shin-ichiro, et al.
Publicado: (2012)

The Emerging Roles of Heterochromatin in Cell Migration
por: Gerlitz, Gabi
Publicado: (2020)

Targeted Delivery of FLT-Morpholino Using Cyclic RGD Peptide
por: Uehara, Hironori, et al.
Publicado: (2017)

Tetrac Delayed the Onset of Ocular Melanoma in an Orthotopic Mouse Model
por: Ashur-Fabian, Osnat, et al.
Publicado: (2019)

The double benefit of Spalax p53: surviving underground hypoxia while defying lung cancer cells in vitro via autophagy and caspase-dependent cell death
por: Ellis, Martin, et al.
Publicado: (2016)

An Efficient Bivalent Cyclic RGD-PIK3CB siRNA Conjugate for Specific Targeted Therapy against Glioblastoma In Vitro and In Vivo
por: Cen, Bohong, et al.
Publicado: (2018)

Radiolabeled Cyclic RGD Peptides as Radiotracers for Imaging Tumors and Thrombosis by SPECT
por: Zhou, Yang, et al.
Publicado: (2011)

The Impact of Induction Regimes on Immune Responses in Patients with Multiple Myeloma
por: Firer, Michael A., et al.
Publicado: (2021)

RGD-conjugated gold nanorods induce radiosensitization in melanoma cancer cells by downregulating α(v)β(3) expression
por: Xu, Wencai, et al.
Publicado: (2012)

Synthesis and Biological Characterization of Monomeric and Tetrameric RGD‐Cryptophycin Conjugates
por: Borbély, Adina, et al.
Publicado: (2020)

Linker Hydrophilicity Modulates the Anticancer Activity of RGD–Cryptophycin Conjugates
por: Anselmi, Michele, et al.
Publicado: (2020)

SETDB1 regulates microtubule dynamics
por: Hernandez‐Vicens, Rosari, et al.
Publicado: (2022)

Synapsin IIb as a functional marker of submissive behavior
por: Nesher, Elimelech, et al.
Publicado: (2015)

Targeted therapy for glioma using cyclic RGD-entrapped polyionic complex nanomicelles
por: Liu, Xiaoying, et al.
Publicado: (2012)

Cyclic RGD-Decorated Liposomal Gossypol AT-101 Targeting for Enhanced Antitumor Effect
por: Liu, Hao, et al.
Publicado: (2022)

Using Attenuated Total Reflection–Fourier Transform Infra-Red (ATR-FTIR) spectroscopy to distinguish between melanoma cells with a different metastatic potential
por: Minnes, Refael, et al.
Publicado: (2017)

FITC-Conjugated Cyclic RGD Peptides as Fluorescent Probes for Staining Integrin α(v)β(3)/α(v)β(5) in Tumor Tissues
por: Zheng, Yumin, et al.
Publicado: (2014)

Synergistic Pro-Apoptotic Effect of a Cyclic RGD Peptide-Conjugated Magnetic Mesoporous Therapeutic Nanosystem on Hepatocellular Carcinoma HepG2 Cells
por: Zhao, Xuanping, et al.
Publicado: (2023)

Conjugates of Cryptophycin and RGD or isoDGR Peptidomimetics for Targeted Drug Delivery
por: Borbély, Adina, et al.
Publicado: (2019)

Synthesis and Biological Evaluation of RGD–Cryptophycin Conjugates for Targeted Drug Delivery
por: Borbély, Adina, et al.
Publicado: (2019)

An iRGD peptide conjugated heparin nanocarrier for gastric cancer therapy
por: Ai, Shichao, et al.
Publicado: (2018)

Linear, Non-Conjugated Cyclic and Conjugated Cyclic Paraphenylene under Pressure
por: Peña-Álvarez, Miriam, et al.
Publicado: (2019)

Thyroid Hormones and Cancer: A Comprehensive Review of Preclinical and Clinical Studies
por: Krashin, Eilon, et al.
Publicado: (2019)

Low thyroid hormone levels improve survival in murine model for ocular melanoma
por: Fabian, Ido Didi, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_4gmgf5klmv0ts8fo8g4eu582h0