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Mapping heterogeneity in patient-derived melanoma cultures by single-cell RNA-seq
Recent technological advances in single-cell genomics make it possible to analyze cellular heterogeneity of tumor samples. Here, we applied single-cell RNA-seq to measure the transcriptomes of 307 single cells cultured from three biopsies of three different patients with a BRAF/NRAS wild type, BRAF...
Autores principales: | Gerber, Tobias, Willscher, Edith, Loeffler-Wirth, Henry, Hopp, Lydia, Schadendorf, Dirk, Schartl, Manfred, Anderegg, Ulf, Camp, Gray, Treutlein, Barbara, Binder, Hans, Kunz, Manfred |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352202/ https://www.ncbi.nlm.nih.gov/pubmed/27903987 http://dx.doi.org/10.18632/oncotarget.13666 |
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