Cargando…

TGFβ1 overexpression is associated with improved survival and low tumor cell proliferation in patients with early-stage pancreatic ductal adenocarcinoma

The role of transforming growth factor beta-type-1 (TGFβ1) in pancreatic ductal adenocarcinoma (PDAC) progression is stage-dependent. We hypothesized that TGFβ1 expression is associated with survival and proliferation markers in patients with early-stage PDAC. We acquired clinicopathologic, treatmen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Glazer, Evan S., Welsh, Eric, Pimiento, Jose M., Teer, Jamie K., Malafa, Mokenge P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352213/ https://www.ncbi.nlm.nih.gov/pubmed/27895310 http://dx.doi.org/10.18632/oncotarget.13533

Ejemplares similares

Prognostic Fifteen-Gene Signature for Early Stage Pancreatic Ductal Adenocarcinoma
por: Chen, Dung-Tsa, et al.
Publicado: (2015)

Neutrophil to lymphocyte ratio, not platelet to lymphocyte or lymphocyte to monocyte ratio, is predictive of patient survival after resection of early-stage pancreatic ductal adenocarcinoma
por: Pointer, David T., et al.
Publicado: (2020)

Overexpression of MUC1 Induces Non-Canonical TGF-β Signaling in Pancreatic Ductal Adenocarcinoma
por: Bose, Mukulika, et al.
Publicado: (2022)

Overexpression of major CDKN3 transcripts is associated with poor survival in lung adenocarcinoma
por: Fan, Chao, et al.
Publicado: (2015)

Overexpression of Mesothelin in Pancreatic Ductal Adenocarcinoma (PDAC)
por: Le, Kai, et al.
Publicado: (2020)

Pancreatic ductal adenocarcinoma staging
por: Al-Hawary, Mahmoud M., et al.
Publicado: (2013)

Expansion of tumor-infiltrating lymphocytes (TIL) from human pancreatic tumors
por: Hall, MacLean, et al.
Publicado: (2016)

Pancreatic Ductal Carcinoma Risk Associated With Hereditary Cancer-Risk Genes
por: Gardiner, Anna, et al.
Publicado: (2022)

SMAD4 and the TGFβ Pathway in Patients with Pancreatic Ductal Adenocarcinoma
por: Dardare, Julie, et al.
Publicado: (2020)

Overexpression of rhophilin 2 promotes pancreatic ductal adenocarcinoma
por: Bo, Wentao, et al.
Publicado: (2021)

Case report: Irreversible electroporation for locally advanced pancreatic cancer
por: Orcutt, Sonia, et al.
Publicado: (2017)

Linc-pint inhibits early stage pancreatic ductal adenocarcinoma growth through TGF-β pathway activation
por: Lu, Huimin, et al.
Publicado: (2019)

Effect of Metformin Use on Survival in Resectable Pancreatic Cancer: A Single-Institution Experience and Review of the Literature
por: Ambe, Chenwi M., et al.
Publicado: (2016)

MCOLN1 Promotes Proliferation and Predicts Poor Survival of Patients with Pancreatic Ductal Adenocarcinoma
por: Hu, Zhan-Dong, et al.
Publicado: (2019)

Thrombospondin-1 overexpression stimulates loss of Smad4 and accelerates malignant behavior via TGF-β signal activation in pancreatic ductal adenocarcinoma
por: Matsumura, Kazuki, et al.
Publicado: (2022)

Murine Pancreatic Adenocarcinoma Reduces Ikaros Expression and Disrupts T Cell Homeostasis
por: Nelson, Nadine, et al.
Publicado: (2015)

Minimally invasive image-guided therapy of primary and metastatic pancreatic cancer
por: Bibok, Andras, et al.
Publicado: (2021)

Plasma Kallikrein-Activated TGF-β Is Prognostic for Poor Overall Survival in Patients with Pancreatic Ductal Adenocarcinoma and Associates with Increased Fibrogenesis
por: Pedersen, Rasmus S., et al.
Publicado: (2022)

Real time ex vivo chemosensitivity assay for pancreatic adenocarcinoma
por: Kim, Dae Won, et al.
Publicado: (2023)

A Phase I Safety, Pharmacokinetic, and Pharmacodynamic Presurgical Trial of Vitamin E δ-tocotrienol in Patients with Pancreatic Ductal Neoplasia
por: Springett, Gregory M., et al.
Publicado: (2015)

TRPM2 promotes the proliferation and invasion of pancreatic ductal adenocarcinoma
por: Lin, Rui, et al.
Publicado: (2018)

Overexpression of PD2 leads to increased tumorigenicity and metastasis in pancreatic ductal adenocarcinoma
por: Vaz, Arokia Priyanka, et al.
Publicado: (2015)

Current Status of the Diagnosis of Early-Stage Pancreatic Ductal Adenocarcinoma
por: Nakaoka, Kazunori, et al.
Publicado: (2023)

Correlation of TNF-α and TGF-β polymorphisms with protein levels in pancreatic ductal adenocarcinoma and colorectal cancer
por: Zagozda, Małgorzata, et al.
Publicado: (2019)

Ral GTPase promotes metastasis of pancreatic ductal adenocarcinoma via elevation of TGF-β1 production
por: Cao, Mingxin, et al.
Publicado: (2023)

Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma
por: Chen, Ru, et al.
Publicado: (2014)

SLPI knockdown induced pancreatic ductal adenocarcinoma cells proliferation and invasion
por: Zhang, Wei, et al.
Publicado: (2015)

Overexpression of GOLPH3 is associated with poor prognosis and clinical progression in pancreatic ductal adenocarcinoma
por: Zhang, Luan-Jing, et al.
Publicado: (2014)

H2A.Z overexpression suppresses senescence and chemosensitivity in pancreatic ductal adenocarcinoma
por: Ávila-López, P. A., et al.
Publicado: (2021)

Clinicopathological Features and Prognosis of Resected Pancreatic Ductal Adenocarcinoma Patients with Claudin-18 Overexpression
por: Park, Sejun, et al.
Publicado: (2023)

Mimics of pancreatic ductal adenocarcinoma
por: Al-Hawary, Mahmoud M., et al.
Publicado: (2013)

Syndecans and Pancreatic Ductal Adenocarcinoma
por: Betriu, Nausika, et al.
Publicado: (2021)

Models of pancreatic ductal adenocarcinoma
por: Dennaoui, Rayane, et al.
Publicado: (2021)

Imaging diagnosis and staging of pancreatic ductal adenocarcinoma: a comprehensive review
por: Elbanna, Khaled Y., et al.
Publicado: (2020)

A new staging system for postoperative prognostication in pancreatic ductal adenocarcinoma
por: Liang, Yuexiang, et al.
Publicado: (2023)

Case Report of Isolated Gastric Metastasis of Pancreatic Cancer From a Diagnostic Biopsy: Management of a Rare Oncologic Entity
por: Rothermel, Luke D., et al.
Publicado: (2020)

Prognostic Estimator of Survival for Patients with Localized and Extended Pancreatic Ductal Adenocarcinoma
por: Gleason, Michael X., et al.
Publicado: (2013)

Evaluation of survival in patients after pancreatic head resection for ductal adenocarcinoma
por: Distler, Marius, et al.
Publicado: (2013)

A Survival Model in Locally Advanced and Metastatic Pancreatic Ductal Adenocarcinoma
por: Wang, Yi, et al.
Publicado: (2018)

CNN-based survival model for pancreatic ductal adenocarcinoma in medical imaging
por: Zhang, Yucheng, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_6cqcagrtcd60q4i2h8da605i3f