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Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9

Wnt/β-catenin signaling elicits context-dependent transcription switches that determine normal development and oncogenesis. These are mediated by the Wnt enhanceosome, a multiprotein complex binding to the Pygo chromatin reader and acting through TCF/LEF-responsive enhancers. Pygo renders this compl...

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Detalles Bibliográficos
Autores principales:	van Tienen, Laurens M, Mieszczanek, Juliusz, Fiedler, Marc, Rutherford, Trevor J, Bienz, Mariann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352222/ https://www.ncbi.nlm.nih.gov/pubmed/28296634 http://dx.doi.org/10.7554/eLife.20882

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