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Involvement of PINK1/parkin-mediated mitophagy in ZnO nanoparticle-induced toxicity in BV-2 cells

With the increasing application of zinc oxide nanoparticles (ZnO NPs) in biological materials, the neurotoxicity caused by these particles has raised serious concerns. However, the underlying molecular mechanisms of the toxic effect of ZnO NPs on brain cells remain unclear. Mitochondrial damage has...

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Detalles Bibliográficos
Autores principales: Wei, Limin, Wang, Jianfeng, Chen, Aijie, Liu, Jia, Feng, Xiaoli, Shao, Longquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352242/
https://www.ncbi.nlm.nih.gov/pubmed/28331313
http://dx.doi.org/10.2147/IJN.S129375