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How to Use the H1 Deep Transcranial Magnetic Stimulation Coil for Conditions Other than Depression

Deep transcranial magnetic stimulation (dTMS) is a relatively new technique that uses different coils for the treatment of different neuropathologies. The coils are made of soft copper windings in multiple planes that lie adjacent to the skull. They are located within a special helmet so that their...

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Autores principales: Tendler, Aron, Roth, Yiftach, Barnea-Ygael, Noam, Zangen, Abraham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352287/
https://www.ncbi.nlm.nih.gov/pubmed/28190035
http://dx.doi.org/10.3791/55100
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author Tendler, Aron
Roth, Yiftach
Barnea-Ygael, Noam
Zangen, Abraham
author_facet Tendler, Aron
Roth, Yiftach
Barnea-Ygael, Noam
Zangen, Abraham
author_sort Tendler, Aron
collection PubMed
description Deep transcranial magnetic stimulation (dTMS) is a relatively new technique that uses different coils for the treatment of different neuropathologies. The coils are made of soft copper windings in multiple planes that lie adjacent to the skull. They are located within a special helmet so that their magnetic fields combine and improve depth penetration. The H1 dTMS coil is designed to stimulate bilateral prefrontal cortices with greater effective stimulation over the left than the right. By positioning the left side of the coil close to the left dorsolateral prefrontal cortex (DLPFC), the H1 coil was used in a multisite study, leading to FDA approval for treatment-resistant depression. In this same position, the H1 coil was also explored as a possible treatment for negative symptoms of schizophrenia, bipolar depression, and migraine. When moved to different positions over the subject's skull, the H1 coil was also explored as a possible treatment for other conditions. Such manipulation of the H1 coil was demonstrated for PTSD and alcohol dependence by positioning it over the medial prefrontal cortex (mPFC), for anxiety by positioning it over the right prefrontal cortex (rPFC), for auditory hallucinations and tinnitus by positioning it over the temporoparietal junction (TPJ), and for Parkinson's and fatigue from multiple sclerosis (MS) by positioning it over the motor cortex (MC) and PFC. Corresponding electrical field diagrams measured with an oscilloscope through a saline-filled head are included.
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spelling pubmed-53522872017-04-04 How to Use the H1 Deep Transcranial Magnetic Stimulation Coil for Conditions Other than Depression Tendler, Aron Roth, Yiftach Barnea-Ygael, Noam Zangen, Abraham J Vis Exp Behavior Deep transcranial magnetic stimulation (dTMS) is a relatively new technique that uses different coils for the treatment of different neuropathologies. The coils are made of soft copper windings in multiple planes that lie adjacent to the skull. They are located within a special helmet so that their magnetic fields combine and improve depth penetration. The H1 dTMS coil is designed to stimulate bilateral prefrontal cortices with greater effective stimulation over the left than the right. By positioning the left side of the coil close to the left dorsolateral prefrontal cortex (DLPFC), the H1 coil was used in a multisite study, leading to FDA approval for treatment-resistant depression. In this same position, the H1 coil was also explored as a possible treatment for negative symptoms of schizophrenia, bipolar depression, and migraine. When moved to different positions over the subject's skull, the H1 coil was also explored as a possible treatment for other conditions. Such manipulation of the H1 coil was demonstrated for PTSD and alcohol dependence by positioning it over the medial prefrontal cortex (mPFC), for anxiety by positioning it over the right prefrontal cortex (rPFC), for auditory hallucinations and tinnitus by positioning it over the temporoparietal junction (TPJ), and for Parkinson's and fatigue from multiple sclerosis (MS) by positioning it over the motor cortex (MC) and PFC. Corresponding electrical field diagrams measured with an oscilloscope through a saline-filled head are included. MyJove Corporation 2017-01-23 /pmc/articles/PMC5352287/ /pubmed/28190035 http://dx.doi.org/10.3791/55100 Text en Copyright © 2017, Journal of Visualized Experiments http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visithttp://creativecommons.org/licenses/by-nc-nd/3.0/
spellingShingle Behavior
Tendler, Aron
Roth, Yiftach
Barnea-Ygael, Noam
Zangen, Abraham
How to Use the H1 Deep Transcranial Magnetic Stimulation Coil for Conditions Other than Depression
title How to Use the H1 Deep Transcranial Magnetic Stimulation Coil for Conditions Other than Depression
title_full How to Use the H1 Deep Transcranial Magnetic Stimulation Coil for Conditions Other than Depression
title_fullStr How to Use the H1 Deep Transcranial Magnetic Stimulation Coil for Conditions Other than Depression
title_full_unstemmed How to Use the H1 Deep Transcranial Magnetic Stimulation Coil for Conditions Other than Depression
title_short How to Use the H1 Deep Transcranial Magnetic Stimulation Coil for Conditions Other than Depression
title_sort how to use the h1 deep transcranial magnetic stimulation coil for conditions other than depression
topic Behavior
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352287/
https://www.ncbi.nlm.nih.gov/pubmed/28190035
http://dx.doi.org/10.3791/55100
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