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Patient-derived ovarian cancer xenografts re-growing after a cisplatinum treatment are less responsive to a second drug re-challenge: a new experimental setting to study response to therapy
Even if ovarian cancer patients are very responsive to a cisplatinum-based therapy, most will relapse with a resistant disease. New experimental animal models are needed to explore the mechanisms of resistance, to better tailor treatment and improve patient prognosis. To address these aims, seven pa...
Autores principales: | Ricci, Francesca, Fratelli, Maddalena, Guffanti, Federica, Porcu, Luca, Spriano, Filippo, Dell’Anna, Tiziana, Fruscio, Robert, Damia, Giovanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352333/ https://www.ncbi.nlm.nih.gov/pubmed/26910918 http://dx.doi.org/10.18632/oncotarget.7465 |
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