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Targeting of interleukin (IL)-17A inhibits PDL1 expression in tumor cells and induces anticancer immunity in an estrogen receptor-negative murine model of breast cancer

The expression of IL-17A and programmed death ligand 1 (PDL1) is increased in estrogen receptor-negative breast cancer. IL-17A promotes tumor cell survival and invasiveness and inhibits the antitumor immune response. The PDL1–PD1 (programmed death protein 1) signaling pathway promotes escape from im...

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Detalles Bibliográficos
Autores principales:	Ma, Yun-Feng, Chen, Chen, Li, Dongqing, Liu, Min, Lv, Zhuang-Wei, Ji, Yanhong, Xu, Jiru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352347/ https://www.ncbi.nlm.nih.gov/pubmed/27935862 http://dx.doi.org/10.18632/oncotarget.13819

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