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Predicting the impact of combined therapies on myeloma cell growth using a hybrid multi-scale agent-based model
Multiple myeloma is a malignant still incurable plasma cell disorder. This is due to refractory disease relapse, immune impairment, and development of multi-drug resistance. The growth of malignant plasma cells is dependent on the bone marrow (BM) microenvironment and evasion of the host's anti...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352350/ https://www.ncbi.nlm.nih.gov/pubmed/28032590 http://dx.doi.org/10.18632/oncotarget.13831 |