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Radiation-induced SOD2 overexpression sensitizes colorectal cancer to radiation while protecting normal tissue

This study investigated whether radiation-induced overexpression of superoxide dismutase 2 (SOD2) exerts radio-sensitizing effects on tumor cells while having radio-protective effects on normal cells during radio-activated gene therapy for human colorectal cancer. A chimeric promoter, C(9)BC, was ge...

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Detalles Bibliográficos
Autores principales:	Zhang, Zhiqiang, Lang, Jinyi, Cao, Zhi, Li, Rong, Wang, Xingyong, Wang, Weidong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352361/ https://www.ncbi.nlm.nih.gov/pubmed/27999194 http://dx.doi.org/10.18632/oncotarget.13954

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