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ASIC1 promotes differentiation of neuroblastoma by negatively regulating Notch signaling pathway
In neurons, up-regulation of Notch activity either inhibits neurite extension or causes retraction of neurites. Conversely, inhibition of Notch1 facilitates neurite extension. Acid-sensing ion channels (ASICs) are a family of proton-gated cation channels, which play critical roles in synaptic plasti...
Autores principales: | Liu, Mingli, Inoue, Koichi, Leng, Tiandong, Zhou, An, Guo, Shanchun, Xiong, Zhi-gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352400/ https://www.ncbi.nlm.nih.gov/pubmed/28030818 http://dx.doi.org/10.18632/oncotarget.14164 |
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