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Aberrant promoter methylation of hOGG1 may be associated with increased risk of non-small cell lung cancer
DNA methylation may epigenetically inactivate tumor suppressor genes in NSCLC. As the human 8-oxoguanine DNA glycosylase (hOGG1) gene promoter is frequently methylated in NSCLC, we evaluated whether genetic or epigenetic alterations of hOGG1 are associated with increased risk of non-small cell lung...
Autores principales: | Qin, Hualong, Zhu, Jianjie, Zeng, Yuanyuan, Du, Wenwen, Shen, Dan, Lei, Zhe, Qian, Qian, Huang, Jian-an, Liu, Zeyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352404/ https://www.ncbi.nlm.nih.gov/pubmed/28039450 http://dx.doi.org/10.18632/oncotarget.14177 |
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