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PREX1 integrates G protein-coupled receptor and phosphoinositide 3-kinase signaling to promote glioblastoma invasion

A defining feature of the brain cancer glioblastoma is its highly invasive nature. When glioblastoma cells are isolated from patients using serum free conditions, they accurately recapitulate this invasive behaviour in animal models. The Rac subclass of Rho GTPases has been shown to promote invasive...

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Detalles Bibliográficos
Autores principales:	Gont, Alexander, Daneshmand, Manijeh, Woulfe, John, Lavictoire, Sylvie J., Lorimer, Ian A.J .
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352422/ https://www.ncbi.nlm.nih.gov/pubmed/28051998 http://dx.doi.org/10.18632/oncotarget.14348

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