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The prognostic value of clonal heterogeneity and quantitative assessment of plasma circulating clonal IG-VDJ sequences at diagnosis in patients with follicular lymphoma
Recent advances in next-generation sequencing (NGS) have enabled the quantitation of circulating tumour DNA (ctDNA) encoding the clonal rearranged V(D)J immunoglobulin locus. We aimed to evaluate the clonal heterogeneity of follicular lymphoma (FL) in the tumour and the plasma at diagnosis and to as...
Autores principales: | Sarkozy, Clémentine, Huet, Sarah, Carlton, Victoria E.H, Fabiani, Bettina, Delmer, Alain, Jardin, Fabrice, Delfau-Larue, Marie-Helene, Hacini, Maya, Ribrag, Vincent, Guidez, Stéphanie, Faham, Malek, Salles, Gilles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352439/ https://www.ncbi.nlm.nih.gov/pubmed/28060738 http://dx.doi.org/10.18632/oncotarget.14448 |
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