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Improvement of the Process Stability of Arylmalonate Decarboxylase by Immobilization for Biocatalytic Profen Synthesis

The enzyme arylmalonate decarboxylase (AMDase) enables the selective synthesis of enantiopure (S)-arylpropinates in a simple single-step decarboxylation of dicarboxylic acid precursors. However, the poor enzyme stability with a half-life time of about 1.2 h under process conditions is a serious limi...

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Detalles Bibliográficos
Autores principales:	Aßmann, Miriam, Mügge, Carolin, Gaßmeyer, Sarah Katharina, Enoki, Junichi, Hilterhaus, Lutz, Kourist, Robert, Liese, Andreas, Kara, Selin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352704/ https://www.ncbi.nlm.nih.gov/pubmed/28360905 http://dx.doi.org/10.3389/fmicb.2017.00448

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