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Age at injury is associated with the long-term cognitive outcome of traumatic brain injuries

INTRODUCTION: The association between age at injury (AAI) and long-term cognitive outcome of traumatic brain injuries (TBI) is debatable. METHODS: Eligible participants with a history of TBI from Alzheimer's Disease Neuroimaging Initiative were divided into a childhood TBI (cTBI) group (the AAI...

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Detalles Bibliográficos
Autores principales: Li, Wei, Risacher, Shannon L., McAllister, Thomas W., Saykin, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352716/
https://www.ncbi.nlm.nih.gov/pubmed/28337475
http://dx.doi.org/10.1016/j.dadm.2017.01.008
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author Li, Wei
Risacher, Shannon L.
McAllister, Thomas W.
Saykin, Andrew J.
author_facet Li, Wei
Risacher, Shannon L.
McAllister, Thomas W.
Saykin, Andrew J.
author_sort Li, Wei
collection PubMed
description INTRODUCTION: The association between age at injury (AAI) and long-term cognitive outcome of traumatic brain injuries (TBI) is debatable. METHODS: Eligible participants with a history of TBI from Alzheimer's Disease Neuroimaging Initiative were divided into a childhood TBI (cTBI) group (the AAI ≤ 21 years old) and an adult TBI (aTBI) group (the AAI > 21 years old). RESULTS: The cTBI group has a higher Everyday Cognition total score than the aTBI group. All perceived cognitive functions are worse for the cTBI group than for the aTBI group except memory. By contrast, the cTBI group has higher assessment scores on either the Boston Naming Test or Rey Auditory Verbal Learning Test than the aTBI group. DISCUSSION: The AAI is associated with the long-term cognitive outcomes in older adults with a history of TBI.
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spelling pubmed-53527162017-03-23 Age at injury is associated with the long-term cognitive outcome of traumatic brain injuries Li, Wei Risacher, Shannon L. McAllister, Thomas W. Saykin, Andrew J. Alzheimers Dement (Amst) Diagnostic Assessment & Prognosis INTRODUCTION: The association between age at injury (AAI) and long-term cognitive outcome of traumatic brain injuries (TBI) is debatable. METHODS: Eligible participants with a history of TBI from Alzheimer's Disease Neuroimaging Initiative were divided into a childhood TBI (cTBI) group (the AAI ≤ 21 years old) and an adult TBI (aTBI) group (the AAI > 21 years old). RESULTS: The cTBI group has a higher Everyday Cognition total score than the aTBI group. All perceived cognitive functions are worse for the cTBI group than for the aTBI group except memory. By contrast, the cTBI group has higher assessment scores on either the Boston Naming Test or Rey Auditory Verbal Learning Test than the aTBI group. DISCUSSION: The AAI is associated with the long-term cognitive outcomes in older adults with a history of TBI. Elsevier 2017-03-02 /pmc/articles/PMC5352716/ /pubmed/28337475 http://dx.doi.org/10.1016/j.dadm.2017.01.008 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Diagnostic Assessment & Prognosis
Li, Wei
Risacher, Shannon L.
McAllister, Thomas W.
Saykin, Andrew J.
Age at injury is associated with the long-term cognitive outcome of traumatic brain injuries
title Age at injury is associated with the long-term cognitive outcome of traumatic brain injuries
title_full Age at injury is associated with the long-term cognitive outcome of traumatic brain injuries
title_fullStr Age at injury is associated with the long-term cognitive outcome of traumatic brain injuries
title_full_unstemmed Age at injury is associated with the long-term cognitive outcome of traumatic brain injuries
title_short Age at injury is associated with the long-term cognitive outcome of traumatic brain injuries
title_sort age at injury is associated with the long-term cognitive outcome of traumatic brain injuries
topic Diagnostic Assessment & Prognosis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352716/
https://www.ncbi.nlm.nih.gov/pubmed/28337475
http://dx.doi.org/10.1016/j.dadm.2017.01.008
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