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Combination of ICP-MS, capillary electrophoresis, and their hyphenation for probing Ru(III) metallodrug–DNA interactions
Determination of the DNA-binding reactivity and affinity is an important part of a successful program for the selection of metallodrug candidates. For such assaying, a range of complementary analytical techniques was proposed and tested here using one of few anticancer metal-based drugs that are cur...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352744/ https://www.ncbi.nlm.nih.gov/pubmed/28116493 http://dx.doi.org/10.1007/s00216-017-0186-0 |