Circulating MicroRNAs as Potential Biomarkers of Atrial Fibrillation

Atrial fibrillation (AF) is the most common supraventricular arrhythmia in the population. MicroRNAs (small endogenous noncoding RNAs) are attractive candidates as biomarkers for AF, especially considering that miRNAs are stable and are detected within easily accessible biofluids such as blood. In t...

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Detalles Bibliográficos
Autores principales: da Silva, Ananília Medeiros Gomes, de Araújo, Jéssica Nayara Góes, de Freitas, Renata Caroline Costa, Silbiger, Vivian Nogueira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352861/
https://www.ncbi.nlm.nih.gov/pubmed/28349066
http://dx.doi.org/10.1155/2017/7804763
Descripción
Sumario:Atrial fibrillation (AF) is the most common supraventricular arrhythmia in the population. MicroRNAs (small endogenous noncoding RNAs) are attractive candidates as biomarkers for AF, especially considering that miRNAs are stable and are detected within easily accessible biofluids such as blood. In this review, we selected twelve studies (2012 to 2016) that were classified according to the sample type. We aimed to provide an overview of the role of circulating miRNAs in AF and to discuss the variability of the results, seeking to improve the perspective of the use of miRNAs as potential noninvasive biomarkers for this heart disease.

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