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Physicochemical and Biological Characterization of the Proposed Biosimilar Tocilizumab

HS628 has been developed as a proposed biosimilar product of originator tocilizumab (Actemra®). An extensive physicochemical and biological characterization was conducted to assess similarity between HS628 and originator tocilizumab. The amino acid sequence was shown to be identical between HS628 an...

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Detalles Bibliográficos
Autores principales: Miao, Shiwei, Fan, Li, Zhao, Liang, Ding, Ding, Liu, Xiaohui, Wang, Haibin, Tan, Wen-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352868/
https://www.ncbi.nlm.nih.gov/pubmed/28349061
http://dx.doi.org/10.1155/2017/4926168