Cargando…
miR-34a mediates oxaliplatin resistance of colorectal cancer cells by inhibiting macroautophagy via transforming growth factor-β/Smad4 pathway
AIM: To investigate whether microRNA (miR)-34a mediates oxaliplatin (OXA) resistance of colorectal cancer (CRC) cells by inhibiting macroautophagy via the transforming growth factor (TGF)-β/Smad4 pathway. METHODS: miR-34a expression levels were detected in CRC tissues and CRC cell lines by quantitat...
Autores principales: | Sun, Chen, Wang, Fu-Jing, Zhang, Hao-Gang, Xu, Xun-Zheng, Jia, Rui-Chun, Yao, Lei, Qiao, Peng-Fei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352922/ https://www.ncbi.nlm.nih.gov/pubmed/28348487 http://dx.doi.org/10.3748/wjg.v23.i10.1816 |
Ejemplares similares
-
lncRNA GAS5 inhibits malignant progression by regulating macroautophagy and forms a negative feedback regulatory loop with the miR-34a/mTOR/SIRT1 pathway in colorectal cancer
por: Zhang, Hao-Gang, et al.
Publicado: (2021) -
Macroautophagy is deregulated in murine and human lupus T lymphocytes
por: Gros, Frédéric, et al.
Publicado: (2012) -
MiR-21, miR-34a, miR-125b, miR-181d and miR-648 levels inversely correlate with MGMT and TP53 expression in primary glioblastoma patients
por: Jesionek-Kupnicka, Dorota, et al.
Publicado: (2017) -
Disruption of microtubules in plants suppresses macroautophagy and triggers starch excess-associated chloroplast autophagy
por: Wang, Yan, et al.
Publicado: (2015) -
MiR-34a overexpression enhances the inhibitory effect of doxorubicin on HepG2 cells
por: Zheng, Shun-Zhen, et al.
Publicado: (2019)