Normative values and contralateral comparison of anterior chamber parameters measured by Pentacam and its correlation with corneal biomechanical factors

PURPOSE: To evaluate the normative values of anterior chamber parameters measured by Pentacam and corneal hysteresis (CH) and corneal resistance factor (CRF) measured by Ocular Response Analyzer (ORA) and their relationship. METHODS: In an observational cross-sectional study, patients aged 18–35 years were included. Exclusion criteria were history of any intraocular or corneal disease, anomaly or surgery; hyperopic spherical refraction more than +3, and myopic spherical refraction less than −5.00 diopters (D) or cylindrical refraction more than 2.00 D. ORA was used to measure CH and CRF. Corneal volume (CV), anterior and posterior Q value (QA and QP), anterior and posterior elevation (AE and PE), central corneal thickness (CCT), corneal thinnest thickness (CTT), anterior chamber depth (ACD), anterior chamber volume (ACV) and anterior chamber angle (ACA) were measured with Pentacam. RESULTS: This study evaluated 506 eyes of 253 cases (182 females) with a mean age of 28.43 ± 6.36 years. The average CH and CRF were 10.07 ± 1.61 and 10.33 ± 1.68 mmHg. CH and CRF were not correlated with PQ, AQ, AE and PE. CH and CRF were significantly correlated with CCT (r = 0.499, p < 0.0001 and r = 0.591, p < 0.0001 respectively), CTT (r = 0.469, p < 0.0001 and r = 0.593, p < 0.0001 respectively) and CV (r = 0.443, p < 0.0001 and r = 0.526, p < 0.0001 respectively). CONCLUSION: A significant positive correlation was found between CH and CRF, and CCT, CTT and CV. This study also provided data about wide range normative values of corneal parameters.