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Assessment of No-Reflow Phenomenon by Myocardial Blush Grade and Pulsed Wave Tissue Doppler Imaging in Patients with Acute Coronary Syndrome
BACKGROUND: No-reflow phenomenon is a complication of myocardial revascularization and it is associated with a worse prognosis. MATERIALS AND METHODS: A prospective study was carried out enrolling patients with acute myocardial infarction (64 patients, 49 male and 15 female, median age 64.9 ± 10.61...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353422/ https://www.ncbi.nlm.nih.gov/pubmed/28465903 http://dx.doi.org/10.4103/2211-4122.135615 |
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author | Novo, Giuseppina Sutera, Maria Rita Di Lisi, Daniela Galifi, Maria Ausilia Fata, Benedetta La Giambanco, Salvatore Arvigo, Luisa Triolo, Oreste Fabio Evola, Salvatore Assennato, Pasquale Novo, Salvatore |
author_facet | Novo, Giuseppina Sutera, Maria Rita Di Lisi, Daniela Galifi, Maria Ausilia Fata, Benedetta La Giambanco, Salvatore Arvigo, Luisa Triolo, Oreste Fabio Evola, Salvatore Assennato, Pasquale Novo, Salvatore |
author_sort | Novo, Giuseppina |
collection | PubMed |
description | BACKGROUND: No-reflow phenomenon is a complication of myocardial revascularization and it is associated with a worse prognosis. MATERIALS AND METHODS: A prospective study was carried out enrolling patients with acute myocardial infarction (64 patients, 49 male and 15 female, median age 64.9 ± 10.61 years), both STEMI and NSTEMI, who underwent myocardial revascularization with percutaneous coronary intervention (PCI). TIMI flow and Myocardial Blush Grade (MBG) were assessed at baseline (T0), in addition to tissue Doppler imaging (TDI) and electrocardiogram. Cardiological evaluation was also performed at T1 (one month after PCI) and T2 (every year after revascularization for a mean follow-up of 24.9 months ± 6.93 months). Patients were divided into two groups on the basis of MBG. RESULTS: In the present study, we found at T1 a significant association between MBG and dyslipidemia (P = 0,038) and NYHA class and MBG (P = 0,040), among clinical variables and cardiovascular risk factors. Moreover, a statistically significant relationship was observed between MBG and a new echocardiographic index of systolic and diastolic dysfunction, the EAS index measured with tissue Doppler imaging (P = 0,013). At T2, the EAS parameter was also significantly impaired in patients with reduced MBG, compared to patients with normal MBG (P = 0,003). CONCLUSIONS: This study demonstrates that the combined evaluation of systolic and diastolic dysfunction by EAS index, according to the literature, could detect a subclinical ventricular dysfunction due to a perfusion defect. Therefore, EAS index could be a useful parameter to be measured in the follow-up of patients undergoing revascularization. |
format | Online Article Text |
id | pubmed-5353422 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-53534222017-05-02 Assessment of No-Reflow Phenomenon by Myocardial Blush Grade and Pulsed Wave Tissue Doppler Imaging in Patients with Acute Coronary Syndrome Novo, Giuseppina Sutera, Maria Rita Di Lisi, Daniela Galifi, Maria Ausilia Fata, Benedetta La Giambanco, Salvatore Arvigo, Luisa Triolo, Oreste Fabio Evola, Salvatore Assennato, Pasquale Novo, Salvatore J Cardiovasc Echogr Original Article BACKGROUND: No-reflow phenomenon is a complication of myocardial revascularization and it is associated with a worse prognosis. MATERIALS AND METHODS: A prospective study was carried out enrolling patients with acute myocardial infarction (64 patients, 49 male and 15 female, median age 64.9 ± 10.61 years), both STEMI and NSTEMI, who underwent myocardial revascularization with percutaneous coronary intervention (PCI). TIMI flow and Myocardial Blush Grade (MBG) were assessed at baseline (T0), in addition to tissue Doppler imaging (TDI) and electrocardiogram. Cardiological evaluation was also performed at T1 (one month after PCI) and T2 (every year after revascularization for a mean follow-up of 24.9 months ± 6.93 months). Patients were divided into two groups on the basis of MBG. RESULTS: In the present study, we found at T1 a significant association between MBG and dyslipidemia (P = 0,038) and NYHA class and MBG (P = 0,040), among clinical variables and cardiovascular risk factors. Moreover, a statistically significant relationship was observed between MBG and a new echocardiographic index of systolic and diastolic dysfunction, the EAS index measured with tissue Doppler imaging (P = 0,013). At T2, the EAS parameter was also significantly impaired in patients with reduced MBG, compared to patients with normal MBG (P = 0,003). CONCLUSIONS: This study demonstrates that the combined evaluation of systolic and diastolic dysfunction by EAS index, according to the literature, could detect a subclinical ventricular dysfunction due to a perfusion defect. Therefore, EAS index could be a useful parameter to be measured in the follow-up of patients undergoing revascularization. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC5353422/ /pubmed/28465903 http://dx.doi.org/10.4103/2211-4122.135615 Text en Copyright: © 2014 Journal of Cardiovascular Echography https://creativecommons.org/licenses/by-nc-sa/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Novo, Giuseppina Sutera, Maria Rita Di Lisi, Daniela Galifi, Maria Ausilia Fata, Benedetta La Giambanco, Salvatore Arvigo, Luisa Triolo, Oreste Fabio Evola, Salvatore Assennato, Pasquale Novo, Salvatore Assessment of No-Reflow Phenomenon by Myocardial Blush Grade and Pulsed Wave Tissue Doppler Imaging in Patients with Acute Coronary Syndrome |
title | Assessment of No-Reflow Phenomenon by Myocardial Blush Grade and Pulsed Wave
Tissue Doppler Imaging in Patients with Acute Coronary Syndrome |
title_full | Assessment of No-Reflow Phenomenon by Myocardial Blush Grade and Pulsed Wave
Tissue Doppler Imaging in Patients with Acute Coronary Syndrome |
title_fullStr | Assessment of No-Reflow Phenomenon by Myocardial Blush Grade and Pulsed Wave
Tissue Doppler Imaging in Patients with Acute Coronary Syndrome |
title_full_unstemmed | Assessment of No-Reflow Phenomenon by Myocardial Blush Grade and Pulsed Wave
Tissue Doppler Imaging in Patients with Acute Coronary Syndrome |
title_short | Assessment of No-Reflow Phenomenon by Myocardial Blush Grade and Pulsed Wave
Tissue Doppler Imaging in Patients with Acute Coronary Syndrome |
title_sort | assessment of no-reflow phenomenon by myocardial blush grade and pulsed wave
tissue doppler imaging in patients with acute coronary syndrome |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353422/ https://www.ncbi.nlm.nih.gov/pubmed/28465903 http://dx.doi.org/10.4103/2211-4122.135615 |
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