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Role of purinergic signaling in experimental pneumococcal meningitis

Excessive neutrophilic inflammation contributes to brain pathology and adverse outcome in pneumococcal meningitis (PM). Recently, we identified the NLRP3 inflammasome/interleukin (IL)-1β pathway as a key driver of inflammation in PM. A critical membrane receptor for NLRP3 inflammasome activation is...

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Detalles Bibliográficos
Autores principales:	Zierhut, Marco, Dyckhoff, Susanne, Masouris, Ilias, Klein, Matthias, Hammerschmidt, Sven, Pfister, Hans-Walter, Ayata, Korcan, Idzko, Marco, Koedel, Uwe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353597/ https://www.ncbi.nlm.nih.gov/pubmed/28300164 http://dx.doi.org/10.1038/srep44625

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