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Structural basis of homo- and heterotrimerization of collagen I
Fibrillar collagen molecules are synthesized as precursors, procollagens, with large propeptide extensions. While a homotrimeric form (three α1 chains) has been reported in embryonic tissues as well as in diseases (cancer, fibrosis, genetic disorders), collagen type I usually occurs as a heterotrime...
Autores principales: | Sharma, Urvashi, Carrique, Loïc, Vadon-Le Goff, Sandrine, Mariano, Natacha, Georges, Rainier-Numa, Delolme, Frederic, Koivunen, Peppi, Myllyharju, Johanna, Moali, Catherine, Aghajari, Nushin, Hulmes, David J. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353611/ https://www.ncbi.nlm.nih.gov/pubmed/28281531 http://dx.doi.org/10.1038/ncomms14671 |
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