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Allosteric modulation of peroxisomal membrane protein recognition by farnesylation of the peroxisomal import receptor PEX19

The transport of peroxisomal membrane proteins (PMPs) requires the soluble PEX19 protein as chaperone and import receptor. Recognition of cargo PMPs by the C-terminal domain (CTD) of PEX19 is required for peroxisome biogenesis in vivo. Farnesylation at a C-terminal CaaX motif in PEX19 enhances the P...

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Detalles Bibliográficos
Autores principales:	Emmanouilidis, Leonidas, Schütz, Ulrike, Tripsianes, Konstantinos, Madl, Tobias, Radke, Juliane, Rucktäschel, Robert, Wilmanns, Matthias, Schliebs, Wolfgang, Erdmann, Ralf, Sattler, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353646/ https://www.ncbi.nlm.nih.gov/pubmed/28281558 http://dx.doi.org/10.1038/ncomms14635

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