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Exonuclease processivity of archaeal replicative DNA polymerase in association with PCNA is expedited by mismatches in DNA
Family B DNA polymerases comprise polymerase and 3′ −>5′ exonuclease domains, and detect a mismatch in a newly synthesized strand to remove it in cooperation with Proliferating cell nuclear antigen (PCNA), which encircles the DNA to provide a molecular platform for efficient protein–protein and p...
Autores principales: | Yoda, Takuya, Tanabe, Maiko, Tsuji, Toshiyuki, Yoda, Takao, Ishino, Sonoko, Shirai, Tsuyoshi, Ishino, Yoshizumi, Takeyama, Haruko, Nishida, Hirokazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353730/ https://www.ncbi.nlm.nih.gov/pubmed/28300173 http://dx.doi.org/10.1038/srep44582 |
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