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Fractional Carbon Dioxide Laser and its Combination with Subcision in Improving Atrophic Acne Scars

BACKGROUND: Acne is a very common skin disease in which scars are seen in 95% of the patients. Although numerous treatments have been recommended, researchers are still searching for a single modality to treat the complication due to its variety in shape and depth. We compared the effects of fractio...

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Autores principales: Nilforoushzadeh, Mohammad Ali, Faghihi, Gita, Jaffary, Fariba, Haftbaradaran, Elaheh, Hoseini, Sayed Mohsen, Mazaheri, Nafiseh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353774/
https://www.ncbi.nlm.nih.gov/pubmed/28349023
http://dx.doi.org/10.4103/2277-9175.201332
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author Nilforoushzadeh, Mohammad Ali
Faghihi, Gita
Jaffary, Fariba
Haftbaradaran, Elaheh
Hoseini, Sayed Mohsen
Mazaheri, Nafiseh
author_facet Nilforoushzadeh, Mohammad Ali
Faghihi, Gita
Jaffary, Fariba
Haftbaradaran, Elaheh
Hoseini, Sayed Mohsen
Mazaheri, Nafiseh
author_sort Nilforoushzadeh, Mohammad Ali
collection PubMed
description BACKGROUND: Acne is a very common skin disease in which scars are seen in 95% of the patients. Although numerous treatments have been recommended, researchers are still searching for a single modality to treat the complication due to its variety in shape and depth. We compared the effects of fractional carbon dioxide (CO(2)) laser alone and in combination with subcision in the treatment of atrophic acne scars. MATERIALS AND METHODS: This clinical trial study was performed in Skin Diseases and Leishmaniasis Research Center (Isfahan, Iran) during 2011–2012. Eligible patients with atrophic acne scars were treated with fractional CO(2) laser alone (five sessions with 3-week interval) on the right side of the face and fractional CO(2) laser plus subcision (one session using both with four sessions of fractional CO(2) laser, with 3-week interval) on the left side. The subjects were visited 1, 2, and 6 months after the treatment. Patient satisfaction rate was analyzed using SPSS 20 software. RESULTS: The average of recovery rate was 54.7% using the combination method and 43.0% using laser alone (P < 0.001). The mean patient satisfaction was significantly higher with the combination method than laser alone (6.6 ± 1.2 vs. 5.2 ± 1.8; P < 0.001). Bruising was only seen with the combination method and lasted for 1 week in 57.0% and for 2 weeks in 43.0%. Erythema was seen in both methods. Postinflammatory pigmentation and hyperpigmentation were associated with combination method. No persistent side effects were seen after 6 months. CONCLUSION: Using a combination of subcision and laser had suitable results regarding scar recovery and satisfaction rate.
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spelling pubmed-53537742017-03-27 Fractional Carbon Dioxide Laser and its Combination with Subcision in Improving Atrophic Acne Scars Nilforoushzadeh, Mohammad Ali Faghihi, Gita Jaffary, Fariba Haftbaradaran, Elaheh Hoseini, Sayed Mohsen Mazaheri, Nafiseh Adv Biomed Res Original Article BACKGROUND: Acne is a very common skin disease in which scars are seen in 95% of the patients. Although numerous treatments have been recommended, researchers are still searching for a single modality to treat the complication due to its variety in shape and depth. We compared the effects of fractional carbon dioxide (CO(2)) laser alone and in combination with subcision in the treatment of atrophic acne scars. MATERIALS AND METHODS: This clinical trial study was performed in Skin Diseases and Leishmaniasis Research Center (Isfahan, Iran) during 2011–2012. Eligible patients with atrophic acne scars were treated with fractional CO(2) laser alone (five sessions with 3-week interval) on the right side of the face and fractional CO(2) laser plus subcision (one session using both with four sessions of fractional CO(2) laser, with 3-week interval) on the left side. The subjects were visited 1, 2, and 6 months after the treatment. Patient satisfaction rate was analyzed using SPSS 20 software. RESULTS: The average of recovery rate was 54.7% using the combination method and 43.0% using laser alone (P < 0.001). The mean patient satisfaction was significantly higher with the combination method than laser alone (6.6 ± 1.2 vs. 5.2 ± 1.8; P < 0.001). Bruising was only seen with the combination method and lasted for 1 week in 57.0% and for 2 weeks in 43.0%. Erythema was seen in both methods. Postinflammatory pigmentation and hyperpigmentation were associated with combination method. No persistent side effects were seen after 6 months. CONCLUSION: Using a combination of subcision and laser had suitable results regarding scar recovery and satisfaction rate. Medknow Publications & Media Pvt Ltd 2017-03-01 /pmc/articles/PMC5353774/ /pubmed/28349023 http://dx.doi.org/10.4103/2277-9175.201332 Text en Copyright: © 2017 Advanced Biomedical Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Nilforoushzadeh, Mohammad Ali
Faghihi, Gita
Jaffary, Fariba
Haftbaradaran, Elaheh
Hoseini, Sayed Mohsen
Mazaheri, Nafiseh
Fractional Carbon Dioxide Laser and its Combination with Subcision in Improving Atrophic Acne Scars
title Fractional Carbon Dioxide Laser and its Combination with Subcision in Improving Atrophic Acne Scars
title_full Fractional Carbon Dioxide Laser and its Combination with Subcision in Improving Atrophic Acne Scars
title_fullStr Fractional Carbon Dioxide Laser and its Combination with Subcision in Improving Atrophic Acne Scars
title_full_unstemmed Fractional Carbon Dioxide Laser and its Combination with Subcision in Improving Atrophic Acne Scars
title_short Fractional Carbon Dioxide Laser and its Combination with Subcision in Improving Atrophic Acne Scars
title_sort fractional carbon dioxide laser and its combination with subcision in improving atrophic acne scars
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353774/
https://www.ncbi.nlm.nih.gov/pubmed/28349023
http://dx.doi.org/10.4103/2277-9175.201332
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