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Interstrain differences in the expression and activity of Cyp2a5 in the mouse liver

BACKGROUND: Cytochrome P450 2A5 (Cyp2a5), a mouse enzyme orthologous of human CYP2A6, catalyzes a number of toxicologically important reactions, including the metabolism of nicotine, aflatoxin B1, and several other xeno- and endobiotics. Cyp2a5 expression is complex and not yet fully understood. We...

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Detalles Bibliográficos
Autores principales:	Poça, Katia S., Parente, Thiago E. M., Chagas, Lucas F., Leal, Bruna S., Leal, Hellen S., Paumgartten, Francisco J. R., De-Oliveira, Ana C. A. X.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353797/ https://www.ncbi.nlm.nih.gov/pubmed/28298240 http://dx.doi.org/10.1186/s13104-017-2435-x

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