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A data-driven approach links microglia to pathology and prognosis in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that lacks a predictive and broadly applicable biomarker. Continued focus on mutation-specific upstream mechanisms has yet to predict disease progression in the clinic. Utilising cellular pathology common to the majority...
Autores principales: | Cooper-Knock, Johnathan, Green, Claire, Altschuler, Gabriel, Wei, Wenbin, Bury, Joanna J., Heath, Paul R., Wyles, Matthew, Gelsthorpe, Catherine, Highley, J. Robin, Lorente-Pons, Alejandro, Beck, Tim, Doyle, Kathryn, Otero, Karel, Traynor, Bryan, Kirby, Janine, Shaw, Pamela J., Hide, Winston |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353945/ https://www.ncbi.nlm.nih.gov/pubmed/28302159 http://dx.doi.org/10.1186/s40478-017-0424-x |
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