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Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during pronuclear development in equine zygotes produced by ICSI
BACKGROUND: Global epigenetic reprogramming is considered to be essential during embryo development to establish totipotency. In the classic model first described in the mouse, the genome-wide DNA demethylation is asymmetric between the paternal and the maternal genome. The paternal genome undergoes...
Autores principales: | Heras, Sonia, Smits, Katrien, De Schauwer, Catharina, Van Soom, Ann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353960/ https://www.ncbi.nlm.nih.gov/pubmed/28331549 http://dx.doi.org/10.1186/s13072-017-0120-x |
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